FUN FACT: You can use 64GB RAM on a Libreboot Dell OptiPlex 3050 Micro, when you install certain CPUs, such as the i3-9100T. Libreboot adds support for these CPUs, unlike Dell firmware.
I tested it today and it works perfectly. I'm using it in my own machine. I now offer 64GB RAM, on the Libreboot 3050 Micro sold here:
https://minifree.org/product/libreboot-3050-micro.html
I'm Libreboot's founder. Sales fund the project. Libreboot replaces proprietary BIOS/UEFI firmware. Debian Linux or your choice of distro/BSD installed.